Direct and constructivist approaches for the design of instruction in well-structured domains: a comparison of efficiency via mental workload and performance.

This doctoral research investigates the efficiency of two instructional designs: a design based on the direct-instruction approach to learning and its extension with a collaborative activity based upon the community of inquiry approach to learning. This is motivated by the educational challenge associated with the improvement of the learning phase. The goal is to investigate the extent to which highly guided communities of inquiry, when added to direct-instruction teaching methods, can actually improve the efficiency of learners. A total of 577 students participated in the experiments across 24 third-level classes that were divided into two groups. A control group of learners attended a delivery based on direct instructional guidelines only, while an experimental group received the same delivery (in equal conditions) extended through a collaborative and inquiring design. Subsequently, learners of each group individually answered a multiple-choice questionnaire (MCQ), from which a performance measure was extracted for the evaluation of the acquired factual, conceptual and procedural knowledge. Two measures of cognitive load (CL) were acquired through self-reporting questionnaires: one unidimensional and one multidimensional. These, in conjunction with the performance measure, contributed to the definition of three measures of efficiency. Statistical evidence shows a positive impact of the experimental layout on the efficiency scores of students, as a consequence of its improvement across three phases: tuning, experimental and refined. The minor contribution to the body of knowledge is a replicable primary research that requalifies an inquiry activity technique, usually employed at primary and secondary levels, as well as other ill-structured domains, in better-structured domains within thirdlevel education. This contribution is connected to a major one that lies in the example of the complementarity between cognitivist direct instructional techniques and social constructivist approaches to teaching and to learning, rather than in the example of their individual, distinct and competitive uses

An Evaluation of the Reliability, Validity and Sensitivity of Three Human Mental Workload Measures Under Different Instructional Conditions in Third-Level Education

Although Cognitive Load Theory (CLT) has been researched for many years, it has been criticised for its theoretical clarity and its methodological approach. A crucial issue is the measurement of three types of cognitive load conceived in the theory, and the assessment of overall human cognitive load during learning tasks. This research study is motivated by these issues and it aims to investigate the reliability, validity and sensitivity of three existing self-reporting mental workload instruments, mainly used in Ergonomics, when applied to Education and in particular to the field of Teaching and Learning. A primary research study has been designed and performed in a typical third-level classroom in Computer Science, and the self-reporting mental workload instruments employed are the NASA Task Load Index, the Workload Profile and the Rating Scale Mental Effort. Three instructional design conditions have been designed and employed for the above purposes. The first design condition followed the traditional explicit instruction paradigm whereby a lecturer delivers instructional material mainly using a one-way approach with almost no interactions with students. The second design condition was inspired by the Cognitive Theory of Multimedia Learning whereby the same content, delivered under the first condition, was converted in a multimedia video by following a set of its design principles. The third design condition was an extension of the second condition whereby an inquiry activity was executed after the delivery of the second condition. The empirical evidence gathered in this study suggests that the three selected mental workload measures are highly reliable. Their moderate face validity is in line with the results obtained so far within Ergonomics emphasising and confirming the difficulty in creating optimally valid measures of mental workload. However, the sensitivity of these measures, as achieved in this study, is low, indicating how the three instructional design conditions, as conceived and implemented, do not impose significantly different mental workload levels on learners

Direct Instruction and Its Extension with a Community of Inquiry: A Comparison of Mental Workload, Performance and Efficiency

This paper investigates the efficiency of two instructional design conditions: a traditional design based on the direct instruction approach to learning and its extension with a collaborative activity based upon the community of inquiry approach to learning. This activity was built upon a set of textual trigger questions to elicit cognitive abilities and support knowledge formation. A total of 115 students participated in the experiments and a number of third-level computer science classes where divided in two groups. A control group of learners received the former instructional design while an experimental group also received the latter design. Subsequently, learners of each group individually answered a multiple-choice questionnaire, from which a performance measure was extracted for the evaluation of the acquired factual, conceptual and procedural knowledge. Two measures of mental workload were acquired through self-reporting questionnaires: one uni-dimensional and one multidimensional. These, in conjunction with the performance measure, contributed to the definition of a measure of efficiency. Evidence showed the positive impact of the added collaborative activity on efficiency

Evaluating instructional designs with mental workload assessments in university classrooms

Cognitive cognitive load theory (CLT) has been conceived for improving instructional design practices. Although researched for many years, one open problem is a clear definition of its cognitive load types and their aggregation towards an index of overall cognitive load. In Ergonomics, the situation is different with plenty of research devoted to the development of robust constructs of mental workload (MWL). By drawing a parallel between CLT and MWL, as well as by integrating relevant theories and measurement techniques from these two fields, this paper is aimed at investigating the reliability, validity and sensitivity of three existing self-reporting mental workload measures when applied to long learning sessions, namely, the NASA Task Load index, the Workload Profile and the Rating Scale Mental Effort, in a typical university classroom. These measures were aimed at serving for the evaluation of two instructional conditions. Evidence suggests these selected measures are reliable and their moderate validity is in line with results obtained within Ergonomics. Additionally, an analysis of their sensitivity by employing the descriptive Harrell-Davis estimator suggests that the Workload Profile is more sensitive than the Nasa Task Load Index and the Rating Scale Mental Effort for long learning sessions

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity